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Products Details
Product Description
– ME-143 is a second-generation tumor-specific inhibitor of NADH oxidase. ME-143 inhibits the WNT/β-catenin pathway in colorectal cancer cells. ME-143 has broadly active against cancers in vitro and in vivo[1].
Web ID
– HY-13675
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H18O4
References
– [1]Pintova S, et al. ME-143 Is Superior to Genistein in Suppression of WNT Signaling in Colon Cancer Cells. Anticancer Res. 2017;37(4):1647-1653.
CAS Number
– 852536-39-1
Molecular Weight
– 334.37
SMILES
– OC1=CC=C2C(C3=CC=C(O)C=C3)C(C4=CC=C(O)C=C4)COC2=C1
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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