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Products Details
Product Description
– MDM2/XIAP-IN-3 (compound 3e) is a dual MDM2/XIAP inhibitor. MDM2/XIAP-IN-3 reduces MDM2 and XIAP protein levels and increases p53 expression, thereby inhibiting cancer cell growth and causing cell death[1].
Web ID
– HY-155571
Shipping
– Room temperature
Molecular Formula
– C29H30N2O5S
References
– [1]Albadari N, et al. Synthesis and biological evaluation of dual MDM2/XIAP inhibitors based on the tetrahydroquinoline scaffold. Eur J Med Chem. 2023 Jul 5;255:115423.
CAS Number
– 2925583-17-9
Molecular Weight
– 518.62
SMILES
– O=S(C1=CC2=C(NC(C3=CC=C(C(C(C)C)=O)C=C3)C4C2OCC4)C=C1)(NC5=CC=CC(C(C)=O)=C5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– IAP;MDM-2/p53
Pathway
– Apoptosis
Product type
– Reference compound
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