Download Files:
Products Details
Product Description
– MDM2-p53-IN-15 is a MDM2-p53 inhibitor with an IC50 value of 26.1 nM. MDM2-p53-IN-15 inhibits the proliferation of various cancer cells and induces cell apoptosis. MDM2-p53-IN-15 can be used for the research of cancer[1].
Web ID
– HY-151172
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C38H26Cl2N6O3
References
– [1]Espadinha M, et al. Discovery of MDM2-p53 and MDM4-p53 protein-protein interactions small molecule dual inhibitors. Eur J Med Chem. 2022 Aug 5;241:114637.
Molecular Weight
– 685.57
SMILES
– O=C(C([C@@H]1C2=CC=CC(O)=C2)=NN(C3=CC=C(Cl)C=C3)[C@@]41C(NC5=C4C=CC(Cl)=C5)=O)NC6=CC=CC(N7N=C(C8=CC=CC=C8)C=C7)=C6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;MDM-2/p53
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
