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MDM2-IN-1
$300 – $2,250
Products Details
Product Description
– MDM2-IN-1 (Compound 30) is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration[1].
Web ID
– HY-130684
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C23H21Cl2FN2O3
References
– [1]Aguilar A, et al. Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro-mannich ring-opening-cyclization reaction mechanism in spiro-oxindoles. J Med Chem. 2014 Dec 26;57(24):10486-98.
CAS Number
– 1410737-09-5
Molecular Weight
– 463.33
Compound Purity
– 99.06
SMILES
– O=C([C@H](N1)[C@H](C2=CC=CC(Cl)=C2F)[C@]3(C(NC4=C3C=CC(Cl)=C4)=O)C51CCCCC5)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMF : 10 mg/mL (ultrasonic;warming;heat to 60°C)|DMSO : 22 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– MDM-2/p53
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
