Download Files:
MD13
SKU
HY-148117-5 mg
Category Reference compound
Tags Cancer, Immunology/Inflammation;PROTAC, Macrophage migration inhibitory factor (MIF);PROTACs
$960
Only 1000 item(s) left in stock.
Products Details
Product Description
– MD13 is a macrophage migration inhibitory factor (MIF)-directed PROTAC with a Ki of 71 nM. MD13 can be used for cancer research[1].
Web ID
– HY-148117
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C35H35N5O8
References
– [1]Xiao Z, et al. Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells. Angew Chem Int Ed Engl. 2021 Aug 2;60(32):17514-17521.
CAS Number
– 2758431-97-7
Molecular Weight
– 653.68
SMILES
– O=C(NC1=CC=C(N2C(OC3=CC(O)=CC=C3C2)=O)C=C1)CCCCCCCNC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Macrophage migration inhibitory factor (MIF);PROTACs
Pathway
– Immunology/Inflammation;PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.