Products Details

Product Description

– MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.

Web ID

– HY-139832

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C25H19N5O4S3

References

– [1]Martínez-González S, et al. Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors. ACS Med Chem Lett. 2021 Nov 2;12(11):1794-1801.

CAS Number

– 1414453-58-9

Molecular Weight

– 549.64

SMILES

– CC1=C(C2=CN=C(OC)C(NS3(=O)=O)=C2)SC4=C1N=CN=C4C5=CC=C(CNC(C6=CC3=CC=C6)=O)S5

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– mTOR;PI3K

Pathway

– PI3K/Akt/mTOR

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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