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Products Details
Product Description
– mCMY020 is a covalent inhibitor of TEAD. mCMY020 effectively reduces YAP (Yes-associated protein)-driven transcription and selectively slows the proliferation of Hippo-deficient cancer cells. mCMY020 can be used in cancer research[1].
Web ID
– HY-157083
Shipping
– Room temperature
Molecular Formula
– C21H21FN4O
References
– [1]Nutsch K, et al. A covalent inhibitor of the YAP-TEAD transcriptional complex identified by high-throughput screening. RSC Chem Biol. 2023 Aug 29;4(11):894-905.
Molecular Weight
– 364.42
SMILES
– C=C(C(NC1=C2N=C(C=CN2N=C1)C3=CC=C(C=C3)C4CCCCC4)=O)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– YAP
Pathway
– Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
