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Products Details
Product Description
– Mcl1-IN-3 is an inhibitor of Mcl1 extracted from patent WO2015153959A2, compound example 57; has an IC50 and Ki of 0.67 and 0.13 μM, respectively.
Web ID
– HY-111468
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H22ClN3O4
References
– [1]Nikolovska-Coleska Z, et al. Pyrazolopyridines as inhibitors of Mcl-1 and and their preparation. WO2015153959A2
CAS Number
– 1814891-79-6
Molecular Weight
– 487.93
SMILES
– CC1=NN(CC2=CC=C(OC3=CC(C)=C(Cl)C(C)=C3)C=C2)C4=C1C(C(O)=O)=CC(C5=CC=CO5)=N4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
