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Products Details
Product Description
– Mcl-1 inhibitor 16 (Compound 9) is a mitochondrial targeting Platinum-based inhibitor of Mcl-1. Mcl-1 inhibitor 1 induces Bax/Bak-dependent apoptosis in cancer cells. Mcl-1 inhibitor 16 can be used alone or together with ABT-199 (HY-15531) and shows anti-tumor activity[1].
Web ID
– HY-155012
Shipping
– Room temperature
Molecular Formula
– C25H29Cl2N3Pt
References
– [1]Lu X, et al. Platinum-Based Mcl-1 Inhibitor Targeting Mitochondria Achieves Enhanced Antitumor Activity as a Single Agent or in Combination with ABT-199. J Med Chem. 2023 Jul 13;66(13):8705-8716.
Molecular Weight
– 637.51
SMILES
– Cl[Pt]1([N](C=CC2=C3N(CCCCCCCCC)C4=CC=CC=C24)=C3C5=CC=CC=[N]51)Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
