Download Files:
Products Details
Product Description
– Mcl-1 inhibitor 14 (Compound (Ra)-10) is an inhibitor of myeloid cell leukemia-1 (MCL-1) with an Ki of 0.018 nM and can be used for anticancer research[1].
Web ID
– HY-154961
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C39H41ClFN5O5S
References
– [1]Demin S, et.al. Macrocyclic Carbon-Linked Pyrazoles As Novel Inhibitors of MCL-1. ACS Med Chem Lett. 2023 Jul 3;14(7):955-961.
Molecular Weight
– 746.29
SMILES
– CN1N=C(C(CSCC2=NN(C)C(CCC3=CC(C=C(C=C4)F)=C4C(OCCCC5=C6C(O)=O)=C3)=C2)=C1C(C(Cl)=CC=C57)=C7N6C)COCCOC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
