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Products Details
Product Description
– Mcl-1 inhibitor 12 (Example 10) is a MCL-1 inhibitor (Ki: 0.22 nM). Mcl-1 inhibitor 12 can be used for the research of cancers[1].
Web ID
– HY-153423
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C47H45ClFN7O6
References
– [1]Jincong Zhuo, et al. 2-((5-(phenyl)-pyrrolo[2,1-f][1,2,4]triazin-4-yl)amino)-3-(phenyl)propanoic acid derivatives and related compounds as mcl-1 enzyme inhibitors for treating cancer. Patent WO2020123994.
CAS Number
– 2445466-24-8
Molecular Weight
– 858.35
SMILES
– COC1=CC=CC=C1C2=NC(COC3=C(C[C@H](C(O)=O)OC4=NC=NN5C4=[C@]([C@]6=C(C)C(Cl)=C(OCCN7CCN(C)CC7)C=C6)C(C8=CC=C(F)C=C8)=C5)C=CC=C3)=CC=N2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family
Isoform
– Mcl-1
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
