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Products Details
Product Description
– MC4171 (compound 34) is a selective KAT8 inhibitor (IC50=8.1 µM). MC4171 has been shown to exhibit moderate micromolar antiproliferative activity in different cancer cell lines, including NSCLC and AML, with potential for studying cancer[1].
Web ID
– HY-153604
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H15N3O3
References
– [1]Fiorentino F, et al. First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8. J Med Chem. 2023 May 25;66(10):6591-6616.
Molecular Weight
– 357.36
SMILES
– O=C(O)C1=CC=C(N2N=C(C3=CC=CC=C3)/C(C2=O)=C/C4=CC=CN4)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Acetyltransferase
Pathway
– Epigenetics
Product type
– Reference compound
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