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Products Details
Product Description
– MC0704 is a STAT3 inhibitor with an IC50 value of 2.13 μM. MC0704 induces cell apoptosis and cell cycle arrest. MC0704 shows antitumor activity in mouse breast cancer models. MC0704 can be used for the research of metastatic triple-negative breast cancer (mTNBC)[1].
Web ID
– HY-148923
Shipping
– Room temperature
Molecular Formula
– C29H21BrN4O2
References
– [1]Byun WS, et al. Design, Synthesis, and Biological Activity of Marinacarboline Analogues as STAT3 Pathway Inhibitors for Docetaxel-Resistant Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):3106-3133.
Molecular Weight
– 537.41
SMILES
– O=C(C1=NC(C(NCCC2=CNC3=C2C=CC=C3)=O)=CC4=C1NC5=CC=CC=C54)C6=CC=C(C=C6)Br
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– STAT
Pathway
– JAK/STAT Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
