Download Files:
Products Details
Product Description
– MC-VC-PAB-Cyclohexanediamine-Thailanstatin A is a Spliceostatin (HY-16466) analog, and a drug-linker conjugates for ADC, consisting of ADC Cytotoxin Thailanstatin A (HY-129589) and cleavable ADC linker (MC-vc-PAB). MC-VC-PAB-Cyclohexanediamine-Thailanstatin A can be used for ADC synthesis[1].
Web ID
– HY-153601
Storage Temperature
– -80°C, protect from light, stored under nitrogen
Shipping
– Dry Ice
Molecular Formula
– C63H91N9O16
References
– [1]Dirico KJ, et al. Preparation of spliceostatin analog antibody conjugates for cancer treatment. World Intellectual Property Organization, WO2014068443 A1. 2014-05-08.
CAS Number
– 1609108-96-4
Molecular Weight
– 1230.45
Compound Purity
– 90.07
SMILES
– O[C@H]1[C@@]2(C[C@H](O[C@@H]1/C=C/C(C)=C/C[C@H]3[C@H](C[C@H]([C@H](O3)C)NC(/C=C[C@H](C)OC(C)=O)=O)C)CC(N[C@@H]4CC[C@H](CC4)NC(OCC5=CC=C(C=C5)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN6C(C=CC6=O)=O)=O)=O)=O)=O)=O)CO2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis;Drug-Linker Conjugates for ADC
Pathway
– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
