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Mc-Val-Cit-PABC-PNP
$50 – $300
Products Details
Product Description
– Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC linker. Mc-Val-Cit-PABC-PNP can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
Web ID
– HY-20336
Storage Temperature
– 4°C (Powder, protect from light, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C35H43N7O11
References
– [1]Che-Leung Law et al. Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders.Patent WO2005081711A2.
CAS Number
– 159857-81-5
Molecular Weight
– 737.76
Compound Purity
– 98.89
SMILES
– CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(OC2=CC=C([N+]([O-])=O)C=C2)=O)C=C1)=O)=O)NC(CCCCCN3C(C=CC3=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 37 mg/mL
Target
– ADC Linker
Isoform
– Cleavable Linker;Protease Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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