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MC-Val-Cit-PAB-vinblastine
$300 – $1,500
Products Details
Product Description
– MC-Val-Cit-PAB-vinblastine is a agent-linker conjugate for ADC with potent antitumor activity by using vinblastine (an microtubule protein inhibitor), linked via the ADC linker MC-Val-Cit-PAB.
Web ID
– HY-128902
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C74H97N10O15
References
– [1]Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.
CAS Number
– 2055896-92-7
Molecular Weight
– 1366.62
Compound Purity
– 90.17
SMILES
– CC[C@@]12[C@@]3([H])[C@]4(CCN3CC=C2)[C@](N(C)C5=CC(OC)=C([C@@]6(C7=C(CC[N@@+]8(CC9=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN%10C(C=CC%10=O)=O)=O)=O)=O)C=C9)C[C@@](C[C@](CC)(O)C8)([H])C6)C%11=CC=CC=C%11N7)C(OC)=O)C=C45)([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug-Linker Conjugates for ADC
Isoform
– Traditional Cytotoxic Agents
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
