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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)
SKU
HY-131990G-Get quote
Category Reference compound
Tags ADC Linker, Antibody-drug Conjugate/ADC Related, Cancer
Products Details
Product Description
– MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Web ID
– HY-131990G
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C28H36N6O10
References
– [1]Masuda, Takeshi, et al. Conjugué anticorps-médicament. WO2014057687A1.
CAS Number
– 1599440-25-1
Molecular Weight
– 616.62
SMILES
– OC(COCNC(CNC([C@@H](NC(CNC(CNC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.