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MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan
$450 – $2,050
Products Details
Product Description
– MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is a agent-linker conjugate for ADC, contains the ADC linker (MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic acid) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan synthesized ADC can be used in study of cancer[1].
Web ID
– HY-147307
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C55H60FN9O13
References
– [1]HUA Haiqing, et al. Antibody-drug conjugate and medical use thereof. Patent WO2021190564A1.
CAS Number
– 2414393-22-7
Molecular Weight
– 1074.12
Compound Purity
– 98.66
SMILES
– O=C(C1(CCC1)OCNC(CNC([C@@H](NC(CNC(CNC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug-Linker Conjugates for ADC
Isoform
– Camptothecins
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
