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Products Details
Product Description
– MC-GGFG-AM-(10NH2-11F-Camptothecin) is an antibody drug conjugates (ADC). MC-GGFG-AM-(10NH2-11F-Camptothecin) binds to the anti-TROp-2 antibody sacituzumab via a hydrolysable pH-sensitive linker and has anti-tumor activity. MC-GGFG-AM-(10NH2-11F-Camptothecin) can be used for cancer research[1].
Web ID
– HY-156514
Shipping
– Room temperature
Molecular Formula
– C45H45FN8O11
References
– [1]Petersen, M. E, et al. Camptothecin analogues, conjugates and methods of use. WO2022246576 A1.2022-01-12.
CAS Number
– 2873460-71-8
Molecular Weight
– 892.88
SMILES
– O=C1N2C(C(C(C2)=CC3=C4)=NC3=CC(F)=C4NC(CNC([C@@H](NC(CNC(CNC(CCCCCN5C(C=CC5=O)=O)=O)=O)=O)CC6=CC=CC=C6)=O)=O)=CC7=C1COC([C@@]7(O)CC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Antibody
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
