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Products Details
Product Description
– Mazaticol is an anticholinergic agent. Mazaticol blocks the muscarinic acetylcholine receptors and cholinergic nerve activity. Mazaticol is a potent 3H-QNB and 3H-PZ binding inhibitor, can bind to the M2 receptors with high affinity. Mazaticol exhibits inhibitory effects on dopamine uptake in the striatal nerve terminal. Mazaticol can be used for parkinsonian syndrome research[1][2].
Web ID
– HY-105793
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C21H27NO3S2
References
– [1]Niimi Y, et al. Mazaticol for Treating Parkinson. 2020.|[2]Katayama S, et al. Effects of anticholinergic antiparkinsonian drugs on binding of muscarinic receptor subtypes in rat brain. Res Commun Chem Pathol Pharmacol. 1990;69(3):261-270.
CAS Number
– 42024-98-6
Molecular Weight
– 405.57
SMILES
– CC1(C)[C@H](N(C)[C@H](CC1)C2)C[C@@H]2OC(C(C3=CC=CS3)(C4=CC=CS4)O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mAChR
Isoform
– mAChR2
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
