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Products Details
Product Description
– MAT2A Allosteric inhibitor 2 is a potent and selective MAT2A allosteric inhibitor with an IC50 of 5 nM. MAT2A Allosteric inhibitor 2 shows nanomolar activity (IC50=5 μM) in the the proliferation assay (MTAP-/- cell line)[1].
Web ID
– HY-155149
Shipping
– Room temperature
Molecular Formula
– C20H17NO3
References
– [1]Tuomo Kalliokoski, et al. Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening. Bioorg Med Chem Lett . 2023 Oct 1;94:129450
CAS Number
– 631897-75-1
Molecular Weight
– 319.35
SMILES
– CC1=CC(OC2=C3C=C(OC)C=C2)=C3C(C4=CC=C(C)C=C4)=[N+]1[O-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Methionine Adenosyltransferase (MAT)
Pathway
– Epigenetics;Metabolic Enzyme/Protease
Product type
– Reference compound
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