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Products Details
Product Description
– MAT2A Allosteric inhibitor 1 (compound 5) is a MAT2A selective inhibitor of methionine adenosyltransferase (MAT) with an IC50 of 6.8 nM[1].
Web ID
– HY-155148
Shipping
– Room temperature
Molecular Formula
– C21H22N6O
References
– [1]Kalliokoski T, et al. Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening. Bioorg Med Chem Lett. 2023 Oct 1;94:129450..
Molecular Weight
– 374.44
SMILES
– CCN1N=C2C(C=CC(NC(C3=CC(C4CC4)=NC5=C3C=NN5CC)=O)=C2)=C1
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Methionine Adenosyltransferase (MAT)
Pathway
– Epigenetics;Metabolic Enzyme/Protease
Product type
– Reference compound
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