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MAT-POS-e194df51-1

SKU HY-157154-Get quote Category Reference compound Tags Anti-infection, Infection, SARS-CoV

Products Details

Product Description

– MAT-POS-e194df51-1 is an orally active, non-covalent and non-peptide SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 value of 37nM. MAT-POS-e194df51-1 is cytotoxic with EC50 values of 64 nM and 126 nM in A549-ACE2-TMPRSS2 cells and HeLa -ACE2 cells, respectively[1].

Web ID

– HY-157154

Shipping

– Room temperature

Molecular Formula

– C24H21ClN4O3S

References

– [1]Boby ML, et al. Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Science. 2023 Nov 10;382(6671):eabo7201.

Molecular Weight

– 480.97

SMILES

– N#CC1(CC1)CS(=O)(N2CC3=C([C@@H](C2)C(NC4=C5C=CC=CC5=CN=C4)=O)C=C(C=C3)Cl)=O

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– SARS-CoV

Pathway

– Anti-infection

Product type

– Reference compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.