Download Files:
MARK-IN-1
$1,680 – $8,550
Products Details
Product Description
– MARK-IN-1 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of <0.25 nM.
Web ID
– HY-101933
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C22H23F2N7OS
References
– [1]Sloman DL, et al. Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4362-6.
CAS Number
– 1109283-93-3
Molecular Weight
– 471.53
SMILES
– O=C(C1=CC(C2=C3N=CC(C4=CN(C)N=C4)=CN3N=C2)=C(C)S1)N[C@H]5C(F)(F)CCC[C@H]5N
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– AMPK
Pathway
– Epigenetics;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
