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Products Details
Product Description
– MAO-B-IN-7 is a potent and blood-brain barrier permeable MAO-B and AChE inhibitor with IC50s of 41 nM, 87 nM and 0.3 μM for human AChE, electric eel AChE and MAO-B, respectively. MAO-B-IN-7 can effectively alleviate oxidative stress and neuroinflammatory damage[1].
Web ID
– HY-146762
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H31NO4
References
– [1]Liu Z, et al. Discovery of novel 3-butyl-6-benzyloxyphthalide Mannich base derivatives as multifunctional agents against Alzheimer’s disease. Bioorg Med Chem.
CAS Number
– 2851012-65-0
Molecular Weight
– 409.52
SMILES
– CCCCC1OC(C2=CC(OCC3=CC(O)=C(C=C3)CN4CCCCC4)=CC=C21)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE);Monoamine Oxidase;Reactive Oxygen Species
Isoform
– AChE;MAO-B
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease;Neuronal Signaling;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
