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Products Details
Product Description
– MAO-B-IN-6 is a potent, selective and orally active MAO-B inhibitor with an IC50 of 0.019 µM. MAO-B-IN-6 shows more efficacious than Safinamide in vitro and in vivo. MAO-B-IN-6 has the potential for the research of parkinson’s disease (PD)[1].
Web ID
– HY-115987
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C19H20F2N2O2
References
– [1]Wang Z,et al. Enhancing monoamine oxidase B inhibitory activity via chiral fluorination: Structure-activity relationship, biological evaluation, and molecular docking study. Eur J Med Chem. 2022; 228:114025.
CAS Number
– 2376198-66-0
Molecular Weight
– 346.37
SMILES
– O=C([C@H]1N(CC2=CC=C(OCC3=CC=CC(F)=C3)C=C2)C[C@@H](F)C1)N
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Monoamine Oxidase
Isoform
– MAO-A;MAO-B
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
