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Products Details
Product Description
– MAO-B-IN-21 is an excellent MAO-B inhibitor with antioxidant activity and anti-Aβ aggregation activity. MAO-B-IN-21 also exhibits metal-ion chelating ability, anti-neuroinflammation (NO, TNF-α), neuroprotective activity and BBB permeability. MAO-B-IN-21 significantly improves the memory and cognitive impairment in Aβ1-42 induced Alzheimer’s disease mice model[1].
Web ID
– HY-149984
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C24H25ClN2O4
References
– [1]Cong S, et al. Discovery of novel 5-(2-hydroxyphenyl)-2-phthalide-3(3H)-pyrazolones as balanced multifunctional agents against Alzheimer’s disease. Eur J Med Chem. 2023 Mar 15;250:115216.
CAS Number
– 2956426-18-7
Molecular Weight
– 440.92
SMILES
– CCCCCCCC1OC(C2=CC(N3N=C(CC3=O)C4=CC(Cl)=CC=C4O)=CC=C21)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Monoamine Oxidase
Isoform
– MAO-B
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
