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Products Details
Product Description
– Mangafodipir, hepatocellular-specific contrast agent, is an efficacious inhibitor of CIPN (chemotherapy-induced peripheral neuropath) and other conditions caused by cellular oxidative stress. Mangafodipir shows no negative interference with the tumoricidal activity of chemotherapy[1][2].
Web ID
– HY-B0993A
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H30MnN4O14P2
References
– [1]Karlsson JOG, et al. Mangafodipir a Selective Cytoprotectant – with Special Reference to Oxaliplatin and Its Association to Chemotherapy-Induced Peripheral Neuropathy (CIPN). Transl Oncol. 2017 Aug;10(4):641-649. |[2]Wang C. Mangafodipir trisodium (MnDPDP)-enhanced magnetic resonance imaging of the liver and pancreas. Acta Radiol Suppl. 1998;415:1-31.
CAS Number
– 155319-91-8
Molecular Weight
– 691.38
SMILES
– O=C1[O-][Mn+2]([N]2(C3)CC4=C5COP([O-])([O-])=O)([O-]C6=C(N=C7)C)([O-]C4=C(N=C5)C)([O-]C3=O)[N](CC6=C7COP([O-])([O-])=O)(CC2)C1.[H+].[H+].[H+].[H+].[H+].[H+]
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Biochemical Assay Reagents
Pathway
– Others
Product type
– Reference compound
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