Download Files:
Products Details
Product Description
– MALT1-IN-8 is a potent MALT1 protease inhibitor with a IC50 of 2 nM. MALT1-IN-8 inhibits the growth of OCI-LY3 lymphoma cells with an IC50 of 1.16 μM. MALT1-IN-8 has anticancer effects (WO2018165385A1; Compound 8)[1].
Web ID
– HY-143426
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H15Cl2N7O
References
– [1]Nathanael S. Gray, et al. Inhibitors of malt1 and uses thereof. WO2018165385A1.
CAS Number
– 2244109-29-1
Molecular Weight
– 440.29
SMILES
– O=C(NC1=CC(Cl)=C(N2N=CC=N2)N=C1)NC3=C(C4CC4)C5=CC(Cl)=CC=C5N=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MALT1
Pathway
– Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
