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Malachite green (hemioxalate)
$50
Only 1000 item(s) left in stock.
Products Details
Product Description
– Malachite green hemioxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo[1][2][3].
Web ID
– HY-D0162
Storage Temperature
– 4°C (Powder, protect from light, stored under nitrogen)
Shipping
– Room Temperature
Molecular Formula
– C23H25N2.1/2C2H2O4.C2HO4
References
– [1]Kozuka S, et, al. Permeability of dormant spores of Bacillus subtilis to malachite green and crystal violet. J Gen Microbiol. 1991 Mar; 137(3): 607-13.|[2]Takahashi S, et, al. Reversible off-on fluorescence probe for hypoxia and imaging of hypoxia-normoxia cycles in live cells. J Am Chem Soc. 2012 Dec 5; 134(48): 19588-91.|[3]Liu T, et, al. Identification of an IKBKE inhibitor with antitumor activity in cancer cells overexpressing IKBKE. Cytokine. 2019 Apr; 116: 78-87.
CAS Number
– 2437-29-8
Molecular Weight
– 463.50
Compound Purity
– 98.0
SMILES
– C/[N+](C)=C1C=C/C(C=C/1)=C(C2=CC=C(N(C)C)C=C2)C3=CC=CC=C3.O=C(O)C([O-])=O.O=C(O)C(O)=O.[1/2]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 10 mg/mL
Target
– Apoptosis;IKK;NF-κB
Pathway
– Apoptosis;NF-κB
Product type
– Dye Reagents
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
