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Mal-VC-PAB-DM1
$320 – $4,000
Products Details
Product Description
– Mal-VC-PAB-DM1 is a agent-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker Mal-VC-PAB [1].
Web ID
– HY-126682
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C61H82ClN9O17
References
– [1]Brian Lannutti, et al. Ror1 antibody immunoconjugates. WO2018237335A1.
CAS Number
– 1464051-44-2
Molecular Weight
– 1248.81
Compound Purity
– 99.12
SMILES
– C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN6C(C=CC6=O)=O)=O)=O)=O)C=C5)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 75 mg/mL (ultrasonic)
Target
– Drug-Linker Conjugates for ADC
Isoform
– Maytansinoids
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
