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Products Details
Product Description
– Mal-PEG8-Val-Ala-PAB-SB-743921 (Compound D7) is a Drug-Linker Conjugates for ADC. Mal-PEG8-Val-Ala-PAB-SB-743921 consists of KSP inhibitor SB-743921 (HY-14661) and a linker. Mal-PEG8-Val-Ala-PAB-SB-743921 can be used for synthesis of ADCs[1].
Web ID
– HY-149416
Shipping
– Room temperature
Molecular Formula
– C73H96ClN7O19
References
– [1]Li Y, et al. A novel antibody-KSP inhibitor conjugate improves KSP inhibitor efficacy in vitro and in vivo. Biomaterials. 2023 Jul 28;301:122258.
Molecular Weight
– 1411.03
SMILES
– O=C1C2=CC=C(Cl)C=C2OC(C(C(C)C)N(C(C3=CC=C(C)C=C3)=O)CCCNC(OCC4=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN5C(C=CC5=O)=O)=O)=O)=O)=O)C=C4)=O)=C1CC6=CC=CC=C6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug-Linker Conjugates for ADC
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
