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Products Details
Product Description
– Mal-Pc is a versatile molecular photosensitizer designed based phthalocyanine and maleimides. Mal-Pc can react with GSH to deplete GSH and reduce aggregation, thereby improving ROS (Reactive Oxygen Species)-mediated effect of photodynamic therapy (PDT) in cancer cells[1].
Web ID
– HY-151940
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C46H28N10O8Si
References
– [1]Juanjuan Chen, et al. Novel molecular photosensitizer with simultaneously GSH depletion, aggregation inhibition and accelerated elimination for improved and safe photodynamic therapy. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114938.
CAS Number
– 2670367-74-3
Molecular Weight
– 876.86
SMILES
– O=C(N1CCC(O[Si]234(OC(CCN5C(C=CC5=O)=O)=O)N6C(C7=C(C6=NC(C8=C9C=CC=C8)=[N]4C9=N%10)C=CC=C7)=NC(C%11=C%12C=CC=C%11)=[N]2C%12=NC%13=C(C=CC=C%14)C%14=C%10N%133)=O)C=CC1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Reactive Oxygen Species
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
