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Mal-C6-α-Amanitin
$1,100 – $17,000
Products Details
Product Description
– Mal-C6-α-Amanitin is a agent-linker conjugate for ADC with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6.
Web ID
– HY-126683
Storage Temperature
– -20°C (Powder, protect from light)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C55H78N12O17S
References
– [1]Brian Lannutti,et al. Ror1 antibody immunoconjugates. WO2018237335A1.
CAS Number
– 1578249-76-9
Molecular Weight
– 1211.34
Compound Purity
– 98.48
SMILES
– O=S1C2=C(C[C@]3([H])NC([C@](NC([C@@]4([H])N(C[C@H](O)C4)C([C@@](CC(N)=O)([H])NC([C@](NC(CNC([C@@]([C@@H](C)CC)([H])NC(CNC3=O)=O)=O)=O)([H])C1)=O)=O)=O)([H])[C@@H](C)[C@@H](O)CO)=O)C5=CC=C(OCCCCCCNC(CCCCCN6C(C=CC6=O)=O)=O)C=C5N2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug-Linker Conjugates for ADC
Isoform
– Daunorubicins/Doxorubicins
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
