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Products Details
Product Description
– Mahanine is a carbazole alkaloid with various biological properties. Mahanine is a potent anticancer agent against different types of cancer cells. Mahanine exhibits antileishmanial activity and can be used for Leishmania infection research research.
Web ID
– HY-121368
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H25NO2
References
– [1]Kaushik Bhattacharya, et al. Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways. Biochem Pharmacol. 2010 Feb 1;79(3):361-72.|[2]Saptarshi Roy, et al. Mahanine exerts in vitro and in vivo antileishmanial activity by modulation of redox homeostasis. Sci Rep
CAS Number
– 28360-49-8
Molecular Weight
– 347.45
SMILES
– OC1=CC2=C(C3=C(N2)C4=C(C(C)=C3)O[C@@](CC/C=C(C)/C)(C)C=C4)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Parasite
Isoform
– Leishmania
Pathway
– Anti-infection
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
