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Products Details
Product Description
– MAGL-IN-8 (compound 13) is a reversible monoacylglycerol lipase (MAGL) inhibitor, with an IC50 of 2.5 ± 0.4 nM for hMAGL[1].
Web ID
– HY-157038
Shipping
– Room temperature
Molecular Formula
– C25H23F3N2O2S
References
– [1]Granchi C, et al. Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors. Eur J Med Chem. 2021 Jan 1;209:112857.
Molecular Weight
– 472.52
SMILES
– O=C(C1=CC=CC(O)=C1)N2CCC(CC3=CC=CC(SC4=NC=CC(C(F)(F)F)=C4)=C3)CC2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– MAGL
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
