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Products Details
Product Description
– mAChR antagonist 1 (compound 4a) is a mAChR antagonist with Ki values of 255 nM, 121 nM, 158 nM, and 255 nM for M1, M3, M4, and M5 subtype, respectively[1].
Web ID
– HY-155367
Shipping
– Room temperature
Molecular Formula
– C19H22N2O2
References
– [1]Marlon Millard, et al. Design, synthesis and preclinical evaluation of muscarine receptor antagonists via a scaffold-hopping approach. Eur J Med Chem. 2023 Oct 21:262:115891.
CAS Number
– 101491-79-6
Molecular Weight
– 310.39
SMILES
– CN1CCC(CC1)OC(N(C2=CC=CC=C2)C3=CC=CC=C3)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mAChR
Isoform
– mAChR1;mAChR2;mAChR3;mAChR4;mAChR5
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
