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Products Details
Product Description
– Maceneolignan H (Compound 8) is a neolignane compound isolated from the arils of Myristica fragrans. Maceneolignan H is a selective CCR3 antagonist (EC50 = 1.4 μM). Maceneolignan H has the potential for the research of allergic diseases[1].
Web ID
– HY-N10397
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C24H30O7
References
– [1]Morikawa T, et al. Neolignans from the Arils of Myristica fragrans as Potent Antagonists of CC Chemokine Receptor 3. J Nat Prod. 2016;79(8):2005-2013.
CAS Number
– 1314042-85-7
Molecular Weight
– 430.49
SMILES
– C[C@@H]([C@@H](C(C=C1)=CC(OC)=C1OC)OC(C)=O)OC(C(OC)=CC(CC=C)=C2)=C2OC
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– CCR
Isoform
– CCR3
Pathway
– GPCR/G Protein;Immunology/Inflammation
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
