Products Details

Product Description

– m7GpppUpG, an oligonucleotide, is an M7GpppNpG trinucleotide cap analogue. m7GpppUpG can be used as a chemical tool enabling manufacturing of RNA featuring either cap 0 or cap 1 structures[1].

Web ID

– HY-145980

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C30H40N12O26P4

References

– [1]Sikorski PJ, et, al. The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5′ cap modulates protein expression in living cells. Nucleic Acids Res. 2020 Feb 28;48(4):1607-1626.

CAS Number

– 2638447-85-3

Molecular Weight

– 1108.60

SMILES

– O=P(O)(OC[C@@H]1[C@@H](OP(O)(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C(NC(N)=NC4=O)=C4N=C3)O2)=O)[C@@H](O)[C@H](N5C(NC(C=C5)=O)=O)O1)OP(OP(OC[C@@H]6[C@@H](O)[C@@H](O)[C@H](N7C(NC(N)=NC8=O)=C8[N+](C)=C7)O6)([O-])=O)(O)=O

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– 10 mM in DMSO

Target

– Nucleoside Antimetabolite/Analog

Pathway

– Cell Cycle/DNA Damage

Product type

– Oligonucleotides

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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