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M62812
$90 – $850
Products Details
Product Description
– M62812 is a toll-like receptor 4 (TLR4) signaling inhibitor. M62812 inhibits endothelial and leukocyte activation and prevents lethal septic shock in mice. M62812 can reduces LPS-induced coagulation and inflammatory responses. M62812 can be used for the research of sepsis[1].
Web ID
– HY-103639A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Molecular Formula
– C13H13Cl2N3OS
References
– [1]Nakamura M, et al. Toll-like receptor 4 signal transduction inhibitor, M62812, suppresses endothelial cell and leukocyte activation and prevents lethal septic shock in mice. Eur J Pharmacol. 2007 Aug 27;569(3):237-43.
CAS Number
– 613263-00-6
Molecular Weight
– 330.23
Compound Purity
– 99.86
SMILES
– NC1=NSC2=C1C=CC(OC3=CC=CC=C3N)=C2.[H]Cl.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 0.1 M HCL : ≥ 50 mg/mL|DMSO : 50 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Toll-like Receptor (TLR)
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
