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M4 mAChR agonist-1
$80 – $350
Products Details
Product Description
– M4 mAChR agonist-1 (compound 10a) is a potent M4 mAChR agonist with an EC50 >10 μM for human M4[1].
Web ID
– HY-147028
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C14H18N4OS
References
– [1]Wood MR, et al. Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core. Bioorg Med Chem Lett. 2016;26(13):3029-3033.
CAS Number
– 785705-53-5
Molecular Weight
– 290.38
Compound Purity
– 99.32
SMILES
– O=C(C1CCN(CC1)C2=C3C(C)=C(C)SC3=NC=N2)N
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 20 mg/mL (ultrasonic;warming;adjust pH to 3 with HCl;heat to 70°C)
Target
– mAChR
Isoform
– mAChR4
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
