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Products Details
Product Description
– m-PEG10-acid is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG10-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
Web ID
– HY-140500
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H44O12
References
– [1]John F. Donovan et al. Pegylated prodrugs of phenolic trpv1 agonists. WO2020023794A1.|[2]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
CAS Number
– 2409969-94-2
Molecular Weight
– 500.58
SMILES
– OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker;PROTAC Linkers
Isoform
– Non-cleavable Linker;PEG Linkers
Pathway
– Antibody-drug Conjugate/ADC Related;PROTAC
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
