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Products Details
Product Description
– LY56110 is an orally active aromatase inhibitor. LY56110 inhibits P-450-dependent p-nitroanisole O-demethylation and ethylmorphine N-demethylation in hepatic microsomes isolated from rat, with the IC50 of 2.5 and 11 μΜ, respectively. LY56110 can be used for neurological disorder study[1][2].
Web ID
– HY-118407
Shipping
– Room temperature
Molecular Formula
– C17H12Cl2N2
References
– [1]O’Neill LA, et al. Effect of estrogen inhibitors on conceptus estrogen synthesis and development in the gilt. Domest Anim Endocrinol. 1991;8(1):139-153.|[2]Lindstrom TD, et al. Disposition of the aromatase inhibitor LY56110 and associated induction and inhibition studies in rats, dogs, and monkeys. Fundam Appl Toxicol. 1987;8(4):595-604.
CAS Number
– 26766-37-0
Molecular Weight
– 315.20
SMILES
– ClC1=CC=C(C=C1)C(C2=CC=C(C=C2)Cl)C3=CN=CN=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cytochrome P450;Monoamine Oxidase
Pathway
– Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
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