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LY5
$190 – $1,150
Products Details
Product Description
– LY5 is a STAT3 inhibitor with an IC50 value of 0.5 μM. LY5 induces apoptosis and inhibits STAT3 phosphorylation. LY5 shows antitumor activity in vivo, it can be used for the research of cancer[1].
Web ID
– HY-12442
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C15H11N3O4S
References
– [1]Yu W, et al. Discovery of novel STAT3 small molecule inhibitors via in silico site-directed fragment-based drug design. J Med Chem. 2013 Jun 13;56(11):4402-12.
CAS Number
– 1436382-03-4
Molecular Weight
– 329.33
SMILES
– NS(=O)(C1=C2C(C(C(NC3=CC=CN=C3)=CC2=O)=O)=CC=C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;STAT
Pathway
– Apoptosis;JAK/STAT Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
