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Products Details
Product Description
– LY43578 is an orally active aromatase inhibitor. LY43578 inhibits P-450-dependent p-nitroanisole O-demethylation and ethylmorphine N-demethylation in hepatic microsomes isolated from rat, with the IC50 of 0.3 and 5 μΜ, respectively. LY43578 can be used for neurological disorder study[1][2].
Web ID
– HY-118178
Shipping
– Room temperature
Molecular Formula
– C17H12Cl2N2O
References
– [1]Lindstrom TD, et al. Disposition of the aromatase inhibitor LY56110 and associated induction and inhibition studies in rats, dogs, and monkeys. Fundam Appl Toxicol. 1987;8(4):595-604.|[2]Gonzalez MI, et al. Injection of an aromatase inhibitor after the critical period of sexual differentiation. Pharmacol Biochem Behav. 1994;47(1):183-186.
CAS Number
– 26766-35-8
Molecular Weight
– 331.20
SMILES
– OC(C1=CC=C(C=C1)Cl)(C2=CN=CN=C2)C3=CC=C(C=C3)Cl
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Cytochrome P450;Monoamine Oxidase
Pathway
– Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
