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LY3177833 (monhydrate)
$132
Only 1000 item(s) left in stock.
Products Details
Product Description
– LY3177833 (Example 4) monhydrate is an orally active CDC7 and pMCM2 inhibitor with IC50 values of 3.3 nM and 290 nM, respectively. LY3177833 monhydrate is a senescence inducer[1][2].
Web ID
– HY-100023A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C16H14FN5O2
References
– [1]Robert Dean Dally, et al. CDC7 Inhibitors. Patent WO2014143601A1.|[2]Li X, et al. First-generation species-selective chemical probes for fluorescence imaging of human senescence-associated β-galactosidase. Chem Sci. 2020 Jun 17;11(28):7292-7301.
CAS Number
– 1627696-53-0
Molecular Weight
– 327.31
Compound Purity
– 99.76
SMILES
– O=C1N[C@@](C)(C2=NC=NC=C2F)C3=C1C=C(C4=CNN=C4)C=C3.[H]O[H]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDC
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
