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LY2794193
$550 – $3,950
Products Details
Product Description
– LY2794193 is a highly potent and selective mGlu3 receptor agonist (hmGlu3 Ki=0.927 nM，EC50=0.47 nM; hmGlu2 Ki=412 nM，EC50=47.5 nM)[1].
Web ID
– HY-119243
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H18N2O6
References
– [1]Monn JA, et al. Synthesis and Pharmacological Characterization of C4β-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 S,2 S,4 S,5 R,6 S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu3 Receptor Agonist. J Med Chem. 2018 Mar 22;61(6):2303-2328.
CAS Number
– 2173037-97-1
Molecular Weight
– 334.32
Compound Purity
– 98.16
SMILES
– O=C([C@@]1(N)[C@]2([H])[C@@H](C(O)=O)[C@]2([H])[C@@H](NC(C3=CC=CC(OC)=C3)=O)C1)O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 200 mg/mL (ultrasonic)|H2O : 2 mg/mL (ultrasonic;adjust pH to 14 with NaOH)
Target
– mGluR
Isoform
– mGluR2;mGluR3
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
