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LY2562175
$130 – $2,300
Products Details
Product Description
– LY2562175 is a potent and selective FXR agonist, with an EC50 of 193 nM[1].
Web ID
– HY-103704
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C28H27Cl2N3O4
References
– [1]Genin MJ, et al. Discovery of 6-(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of Dyslipidemia. J Med Chem. 2015 Dec 24;58(24):9768-72.
CAS Number
– 1103500-20-4
Molecular Weight
– 540.44
Compound Purity
– 99.26
SMILES
– O=C(C1=CN(C)C2=C1C=CC(N3CCC(OCC4=C(C5CC5)ON=C4C6=C(Cl)C=CC=C6Cl)CC3)=C2)O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 62.5 mg/mL (ultrasonic)
Target
– Autophagy;FXR
Pathway
– Autophagy;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
