LY2562175

$130$2,300

Products Details

Product Description

– LY2562175 is a potent and selective FXR agonist, with an EC50 of 193 nM[1].

Web ID

– HY-103704

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C28H27Cl2N3O4

References

– [1]Genin MJ, et al. Discovery of 6-(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of Dyslipidemia. J Med Chem. 2015 Dec 24;58(24):9768-72.

CAS Number

– 1103500-20-4

Molecular Weight

– 540.44

Compound Purity

– 99.26

SMILES

– O=C(C1=CN(C)C2=C1C=CC(N3CCC(OCC4=C(C5CC5)ON=C4C6=C(Cl)C=CC=C6Cl)CC3)=C2)O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– DMSO : 62.5 mg/mL (ultrasonic)

Target

– Autophagy;FXR

Pathway

– Autophagy;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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