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LY2409881
$132 – $1,092
Products Details
Product Description
– LY2409881 is a selective IκB kinase β (IKK2) inhibitor with an IC50 of 30 nM.
Web ID
– HY-B0788
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H29ClN6OS
Citations
– Int J Mol Sci. 2023, 24(1), 320.|Clin Transl Med. 2022 Jun;12(6):e850.
References
– [1]Deng C, et al. The novel IKK2 inhibitor LY2409881 potently synergizes with histone deacetylase inhibitors in preclinical models of lymphoma through the downregulation of NF-κB. Clin Cancer Res. 2015 Jan 1;21(1):134-45.
CAS Number
– 946518-61-2
Molecular Weight
– 485.04
SMILES
– O=C(C1=C(C=C(C2=NC(NCCCN3CCN(C)CC3)=NC=C2Cl)S4)C4=CC=C1)NC5CC5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 37 mg/mL
Target
– IKK
Isoform
– IKK-β
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
